Hyperbaric Oxygen Therapy (HBOT) Research for Carcinoma.
Abstract: The effect of chronic anemia on tumor radiosensitivity in a murine tumor has been investigated. Anemia was induced by bilateral kidney irradiation given several months before tumor implantation. Anemic, anemic transfused, and normal non-anemic age-matched...
Abstract: This study deals with in vitro chemosensitivity testing of squamous cell carcinoma of the head and neck by measuring the drug-induced inhibition of [3H]thymidine incorporation. Cell suspensions and tumour slices obtained from four human tumour xenografts...
Abstract: Ravelo, Marx, , , , , , , (). [Induced regression of established buccal carcinomas and suppression of dysplastic changes in the oral mucosa using oxygen radical generating systems: an objective study of glucose oxidase, horseradish peroxidase and hyperbaric...
Abstract: This report describes experience with radiation therapy in hyperbaric oxygen in 201 patients with squamous carcinoma arising in the mobile portion of tongue (anterior 2/3), oropharynx, hypopharynx, and supraglottic larynx, treated between the years 1964 and...
Abstract: Traumatic, clostridial myonecrosis is a rare and serious complication of wounds. Nontraumatic, metastatic, clostridial myonecrosis may be caused by carcinoma of the large intestine. Nontraumatic myonecrosis becomes evident with localized pain, generalized...
Abstract: It is proposed that hyperbaric oxygen fails in the clinical situation due to a high proportion (greater than 33%) of hypoxic cells in human tumours. The means of overcoming this problem are reviewed. Additional to hyperbaric oxygenation, moderate hypothermia...
Abstract: Physicians are aware of the association between massively contaminated wounds and clostridial myonecrosis, or gas gangrene. A far less common but equally devastating presentation is that of nontraumatic or spontaneous gas gangrene. The most frequently...
Abstract: 104 patients with head and neck cancer were entered into a prospective controlled trial of radiotherapy in hyperbaric oxygen (HBO). The trial compared 10 fractions of radiotherapy in HBO with 30 fractions of radiotherapy in air. Survival and local control...
Abstract: One hundred and thirty patients with locally advanced squamous carcinoma of the head and neck were treated in a prospective randomized trial to compare conventional irradiation (63.00 Gy in 30 fractions) with a combination sensitizer regimen of misonidazole...